APIGENIN CAUSES BIOCHEMICAL MODULATION, GLUT4 AND CD38 ALTERATIONS TO IMPROVE DIABETES AND TO PROTECT DAMAGES OF SOME VITAL ORGANS IN EXPERIMENTAL DIABETES

@article{Hossain2014APIGENINCB,
  title={APIGENIN CAUSES BIOCHEMICAL MODULATION, GLUT4 AND CD38 ALTERATIONS TO IMPROVE DIABETES AND TO PROTECT DAMAGES OF SOME VITAL ORGANS IN EXPERIMENTAL DIABETES},
  author={C. M. Hossain and M. K. Ghosh and B. Satapathy and N. S. Dey and B. Mukherjee},
  journal={American Journal of Pharmacology and Toxicology},
  year={2014},
  volume={9},
  pages={39-52}
}
Diabetes mellitus gradually leads to dysfunction an d failure of some vital organs specially the eyes, kidneys, pancreas, brain, heart, liver and lungs. The study was aimed to evaluate the antidiabetic potential of apigenin and its mechanistic role in controlling damages of vital tissues in streptozotocin-induced diabetic ra ts. Streptozotocin-induced diabetic rats were treated w ith apigenin and glipizide. Various biochemical cha nges, GLUT4 and CD38 protein expression patterns and… Expand
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