API Determination by NIR Spectroscopy Across Pharmaceutical Production Process


The purpose of this research was to demonstrate the ability of reflectance near-infrared (NIR) spectroscopy for quantitative analysis of an active ingredient in different production steps of a solid formulation. The drug is quantified at two different steps of a pharmaceutical process: after granulation and after tablet coating. Calibration samples were… (More)
DOI: 10.1208/s12249-008-9156-3


5 Figures and Tables