APC targeting enhances immunogenicity of a novel multistage Fc-fusion tuberculosis vaccine in mice

Abstract

Numerous studies have demonstrated that targeting immunogens to FcγR on antigen-presenting cells (APCs) can selectively uptake and increase cellular immunity in vitro and in vivo. Therefore, the present study was conducted to evaluate immunogenicity of a novel multistage tuberculosis vaccine, a combination of an early and a dormant immunogenic protein… (More)
DOI: 10.1007/s00253-015-6952-z

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