APC E1317Q is not associated with Colorectal Cancer in a population-based case-control study in Northern Israel.

@article{Rozek2006APCEI,
  title={APC E1317Q is not associated with Colorectal Cancer in a population-based case-control study in Northern Israel.},
  author={Laura S. Rozek and Gadi Rennert and Stephen B. Gruber},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  year={2006},
  volume={15 11},
  pages={2325-7}
}
A variant in the adenomatous polyposis coli gene, APC E1317Q, has been inconsistently associated with risk of colorectal cancer. We used data collected as a part of the Molecular Epidemiology of Colorectal Cancer study, a population-based study of colorectal cancer in northern Israel (1,834 matched cases and controls), to evaluate the relationship between this variant and risk of sporadic colorectal cancer. There was no association between E1317Q and colorectal cancer [odds ratio (OR), 1.15; 95… CONTINUE READING

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