AP1 binding site is another target of FGF2 regulation of bone sialoprotein gene transcription.


Bone sialoprotein (BSP) is an early marker of osteoblast differentiation. We previously reported that fibroblast growth factor 2 (FGF2) regulates BSP gene transcription via FGF2 response element (FRE) in the proximal promoter of rat BSP gene. We here report that activator protein 1 (AP1) binding site overlapping with glucocorticoid response element (GRE… (More)
DOI: 10.1016/j.gene.2007.11.017


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