AP-1 stimulates the cathepsin K promoter in RAW 264.7 cells.

@article{Pang2007AP1ST,
  title={AP-1 stimulates the cathepsin K promoter in RAW 264.7 cells.},
  author={Manhui Pang and Ariel F. Martinez and Isabel C. Delgado Fern{\'a}ndez and Wayne E Balkan and Bruce Robert Troen},
  journal={Gene},
  year={2007},
  volume={403 1-2},
  pages={
          151-8
        }
}
Cathepsin K (CTSK) is a secreted protease that plays an essential role in osteoclastic bone resorption, and CTSK levels increase with osteoclast differentiation and activation, a process that is controlled by a complex physiological network of hormones and cytokines. A critical regulator of this process is receptor activator of NF-kappaB ligand (RANKL), a member of the tumor necrosis factor (TNF) superfamily of cytokines that can act via the TNF receptor activating factor (TRAF6)/AP-1 signaling… CONTINUE READING

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