• Corpus ID: 12769103

ANTIMICROBIAL RESISTANCE IN G7 COUNTRIES AND BEYOND: Economic Issues, Policies and Options for Action

  title={ANTIMICROBIAL RESISTANCE IN G7 COUNTRIES AND BEYOND: Economic Issues, Policies and Options for Action},
  author={Michele Cecchini and Juliane Langer and Luke Slawomirski},

An Ambitious USG Advanced Commitment for Subscription-Based Purchasing of Novel Antimicrobials and Its Expected Return on Investment

Anti-microbial drugs form the backbone of modern medicine. Yet their lifespan is naturally limited; over time, use of these drugs selects for mutations that survive exposure those same drugs, driving

Solid and solution properties of the antimicrobial agent clofazimine

.............................................................................................................................................. VIII PUBLICATIONS

A One Health Framework to Estimate Costs of Antimicrobial Resistance

This is the first full AMR costing framework to be developed for bacterial pathogens in human and animal health and the environment and represents a first step towards more comprehensive analyses for comparing cost-effectiveness of AMR interventions at the local level as well as more harmonised analyses at the global level.

Polish River Basins and Lakes – Part II: Biological Status and Water Management

This study presents the results of a long-term study of periphyton inhabiting submerged parts of shoots of Phragites australis, carried out in the ecosystems of northern Poland (lakes, rivers, oxbows

Socioeconomic Factors and Use of Antibiotics by Dairy Farmers vis-a-vis Antibiotic Resistance

An updated preclinical paradigm is needed to assess the risk of resistance development in early preclinical development and is feasible and is not limited by methodology but rather by tradition.

Activity of metabolites produced by new strains of Lactobacillus in modified de Man, Rogosa and Sharpe (MRS) medium against multidrug-resistant bacteria

The activity of metabolites produced by new strains of Lactobacillus against multidrug-resistant bacteria was investigated and organic acids and ethanol are likely to be responsible for this antimicrobial activity.

Delinking Investment in Antibiotic Research and Development from Sales Revenues: The Challenges of Transforming a Promising Idea into Reality

Kevin Outterson and colleagues outline a model to address access, conservation, and innovation of antibiotics and suggest a three-pronged approach to achieve this goal.

The Antimicrobial Effect of Various Single-Strain and Multi-Strain Probiotics, Dietary Supplements or Other Beneficial Microbes against Common Clinical Wound Pathogens

It is found that the multi-strains dietary supplements exhibited a statistically significant higher antagonistic effect against the challenge wound pathogens than the single-strain microbes and that lactobacilli-containing dietary supplements and single-Strain microbes were significantly more efficient than the selected propionibacteria and bacilli.



Comparison of mortality associated with methicillin-resistant and methicillin-susceptible Staphylococcus aureus bacteremia: a meta-analysis.

A meta-analysis was performed to summarize the impact of methicillin-resistance on mortality in Staphylococcus aureus bacteremia and explored the reasons for heterogeneity by means of subgroup analyses.

The impact of pricing and patent expiration on demand for pharmaceuticals: an examination of the use of broad-spectrum antimicrobials

  • K. Kaier
  • Medicine
    Health Economics, Policy and Law
  • 2012
It is concluded that price dependence of demand for antimicrobials is present both in the ambulatory and the hospital setting, however, this is especially surprising in the hospitalSetting because price differences among the antibiotics observed are particularly small compared with the overall cost of hospitalisation.

Creating an intergovernmental consortium for new antibiotics: a new development

  • drugs”, Health Affairs (Millwood),
  • 2015

Mortality and delay in effective therapy associated with extended-spectrum beta-lactamase production in Enterobacteriaceae bacteraemia: a systematic review and meta-analysis.

In Enterobacteriaceae bacteraemia, ESBL production is associated with increased mortality and delay in effective therapy, however, lack of controlled studies limits interpretation regarding causality, and further controlled studies are required.

Demand systems and the true subindex of the cost of living for pharmaceuticals

This paper investigates the demand for prescription pharmaceuticals at the retail level. We use complete demand systems to investigate elasticity for major classes of pharmaceuticals. We estimate

Characteristics of Demand for Antibiotics in Primary Care: An Almost Ideal Demand System Approach

The larger use of more expensive antibiotics is also associated with the self-dispensing status of practices, ceteris paribus, and elasticities between newer/more expensive generations and older/less expensive generations of antibiotics are found.

On the Future of Drug Discovery