author={Margaret R. Hammerschlag and Christine C. Dykstra and Daniel R. Mcclernon and Richard R. Tidwell and Gianni Balliano and Paola Milla and Maurizio Ceruti and Franca Viola and Paola Brusa and Luigi Cattel and Jean-Nicolas Volff and Dominique Vandewiele},
  journal={Antimicrobial Agents and Chemotherapy},
  pages={1 - 22}
Limit the abstract to 250 words or fewer and concisely summarize the basic content of the paper without presenting extensive experimental details. Avoid abbreviations and references, and do not include diagrams. When it is essential to include a reference, use the same format as shown for the References section but omit the article title. Conclude the abstract with a summary statement. Because the abstract will be published separately by abstracting services, it must be complete and… 
What Can One Learn That is Clinically Relevant from the Results of in vitro Studies on Persisters ?
  • Biology
The work of Abel zur Wiesch et al. (8) describes a testable model in which the presence of " persisters " in vitro can be explained solely by classic chemical kinetics involving the interaction between antibiotic and its target molecule.
Melioidosis: Antibiogram of cases in Brunei Darussalam
Imipenem, meropenem, ceftazidime, piperacillin and chloramphenicol have remained to be the effective drugs for the treatment of Melioidosis over the study period.
Surveillance of susceptibility profile to antiseptics in ITU isolates of Staphylococcus aureus, including MRSA
It can be concluded from this study that AHRs are unlikely to kill all microbial flora on HCWs hands, and recommendations have been made to improve hand hygiene practices and the efficacy of A HRs used in ITUs.
A contribution to the study of biocontrol agents apitherapy and other potential alternatives to antibiotics
The overall aim of the study was to add further the authors' knowledge of some of these alternatives to antibiotics, concentrating on maggot therapy, apitherapy and to a lesser extent mycotherapy, as well as in vitro antibacterial activity of tamarind.
Moxalactam (Latamoxef)
Moxalactam has moderate activity against Pseudomonas aeruginosa, but on the basis of present evidence can not be recommended as sole antibiotic treatment of known or suspected pseudomonal infections and has the advantage of being devoid of nephrotoxicity.
CYP51 as drug targets for fungi and protozoan parasites: past, present and future
The history of antifungal azoles, the situation with the current clinical azole-based drugs, and the attempts of their repurposing for treatment of human infections with the protozoan parasites that, similar to fungi, also produce endogenous sterols are described.
Synthesis and antitubercular evaluation of new 1,2,3-triazole derivatives of carbohydrates
The preparation of novel 1,4-disubstituted-1,2,3-triazoles derivatives from D-glucose and D-fructose and their in vitro antibacterial activity against Mycobacterium tuberculosis were evaluated.
Studies on multi_drug resistance in urinary tract infection patients
The distribution and antibiotic susceptibility patterns of bacterial strains isolated from patients with community acquired urinary tract infections at Aligarh hospital in India as well as identification of ESBL producers in the population of E. coli and Klebsiella spp.
Title In Vitro and In Vivo Efficacy of an LpxC Inhibitor , CHIR-090 , Alone or Combined with Colistin against Pseudomonas aeruginosa Biofilm
The combination of colistin and CHIR090 at subinhibitory concentrations demonstrated synergistic activity both in vivo and in vitro and prevented the formation of Colistin-tolerant subpopulations in in vitro biofilms.
Characterisation of the chemical basis of T-cell mediated β-lactam hypersensitivity reactions
A novel mass spectrometric method was developed to quantify the level of piperacillin protein binding needed to activate T-cells and it was estimated that 2.8% modification of albumin is sufficient for effective T-cell activation.


Use of International Units When Dosing Colistin Will Help Decrease Confusion Related to Various Formulations of the Drug around the World
The issue of daily dosage of intravenouscolistin is clarified to help clinicians with the confusion regarding the recommended dosage of colistin on the two sides of the Atlantic Ocean.
Bergey’s Manual® of Systematic Bacteriology
BCL3 and Sheehy cite Bergey's manual of determinative bacteriology of which systematic bacteriology, first edition, is an expansion. With v.4 the set is complete. The volumes cover, roughly, v.1, the
Effect of Subtherapeutic Administration of Antibiotics on the Prevalence of Antibiotic-Resistant Escherichia coli Bacteria in Feedlot Cattle
The findings of the present study indicated that subtherapeutic administration of tetracycline in combination with sulfamethazine increased the prevalence of tET- and AMP-resistant E. coli in cattle.
Competency Assessment in the Clinical Microbiology Laboratory
Competency assessment programs must not only meet the letter of the law but also find a way to make these assessments meaningful, instructive, and able to detect areas of concern.
How Do You Improve Compliance?
General principles to improve compliance in pediatrics by improving communication and characteristics of the practice setting are provided and a one-on-one relationship between physician and patient is needed for communication and improved compliance.
Nitrate-Dependent Regulation of Acetate Biosynthesis and Nitrate Respiration by Clostridium thermoaceticum
The results indicate that nitrate coordinately represses genes encoding enzymes and electron transport proteins in the Wood-Ljungdahl pathway and activates transcription of nitrate respiratory proteins.
Polar residues drive association of polyleucine transmembrane helices
Results show that polyleucine sequences with Asn, Asp, Gln, Glu, and His, residues capable of being simultaneously hydrogen bond donors and acceptors, form homo- or heterooligomers, and interactions between polar residues in the helices of transmembrane proteins may serve to provide structural stability and oligomerization specificity.
Screening the fruitfly immune system
The anti-microbial defense system of Drosophila shows functional similarities with the vertebrate innate immune system, as well as a large number of immune-regulated genes with unknown immunological function.
Persistent Transactivation by Meis1 Replaces Hox Function in Myeloid Leukemogenesis Models: Evidence for Co-Occupancy of Meis1-Pbx and Hox-Pbx Complexes on Promoters of Leukemia-Associated Genes
Surprisingly, Vp16-Meis1 functioned as an autonomous oncoprotein that mimicked combined activities of Meis1 plus Hoxa9, immortalizing early progenitors, inducing low-level expression of MeIS1-related signature genes, and causing leukemia without coexpression of exogenous or endogenous Hox genes.
Genus I. Thermus Brock and Freeze
  • 1969