Effect of graded doses of nicotine on ovarian and uterine activities in albino rats
- S. Patil, B. Bhaktaraj, S. B. Patil
- Indian J. Exp. Biol.,
Oral feeding of 70% EtOH extract of Lindenbergia indica to female rats at the dose of 500 mg/kg body weight and 1000 mg / kg body weight caused significant reduction of serum cholesterol, HDL - cholesterol, triglycerides & phospholipids (P≤ 0.05 to P≤ 0.001). Where as the protein levels were not reduced significantly.Fertility test showed 100% negative results. The negative fertility reflects the arrest of Oogenesis & depletion of estrogen level. Further Lindenbergia indica reflects antiestrogenic nature.