ANGPTL4 expression induced by butyrate and rosiglitazone in human intestinal epithelial cells utilizes independent pathways.

@article{Korecka2013ANGPTL4EI,
  title={ANGPTL4 expression induced by butyrate and rosiglitazone in human intestinal epithelial cells utilizes independent pathways.},
  author={Agata Korecka and Tomas de Wouters and Antonietta Cultrone and Nicolas Lapaque and Sven Pettersson and Jo{\"e}l Dore and Herv{\'e} M Blotti{\`e}re and Velmurugesan Arulampalam},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  year={2013},
  volume={304 11},
  pages={G1025-37}
}
Short-chain fatty acids (SCFAs), such as butyrate and propionate, are metabolic products of carbohydrate fermentation by the microbiota and constitute the main source of energy for host colonocytes. SCFAs are also important for gastrointestinal health, immunity, and host metabolism. Intestinally produced angiopoietin-like protein 4 (ANGPTL4) is a secreted protein with metabolism-altering properties and may offer a route by which microbiota can regulate host metabolism. Peroxisome proliferator… CONTINUE READING