ANCA-negative pauci-immune renal vasculitis: histology and outcome.

  title={ANCA-negative pauci-immune renal vasculitis: histology and outcome.},
  author={Ute Eisenberger and Fadi Fakhouri and Philippe Vanhille and H{\'e}l{\`e}ne Beaufils and Alfred Mahr and Lo{\"i}c Guillevin and Philippe Lesavre and L H No{\"e}l},
  journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association},
  volume={20 7},
BACKGROUND Pauci-immune renal vasculitis with focal glomerular necrosis and crescent formation is usually associated with anti-neutrophil cytoplasmic antibodies (ANCAs). However, ANCA's are absent in up to 10% of cases, which constitutes a rarely studied variant of renal vasculitis. METHODS This retrospective multicentre cohort study analyzed the presenting features, renal histology and outcome in 20 patients with pauci-immune crescentic necrotizing renal vasculitis in whom indirect… CONTINUE READING