AN ACTION SPECTRUM FOR UV PHOTOCARCINOGENESIS *

@article{Cole1986ANAS,
  title={AN ACTION SPECTRUM FOR UV PHOTOCARCINOGENESIS *},
  author={Curtis A Cole and Paul Donald Forbes and Ronald Edgar Davies},
  journal={Photochemistry and Photobiology},
  year={1986},
  volume={43}
}
Abstract— Hairless mice were irradiated repeatedly by exposure to unfiltered black‐light (FR74T12 PUVA) fluorescent lamps and the time to development of skin tumors was determined. For several groups of animals the treatment variable was the size of the weekly dose. A similar approach had been used previously to determine dose‐response characteristics for other ultraviolet radiation emitting sources: a xenon arc solar simulator (with a series of five cut‐off filters producing five source… 

AN ACTION SPECTRUM FOR ULTRAVIOLET INDUCED ELASTOSIS IN HAIRLESS MICE: QUANTIFICATION OF ELASTOSIS BY IMAGE ANALYSIS

TLDR
The erythema spectrum was the most predictive for elastosis except that the longer UVA wavelengths were less effective forElastosis than for ery thema, and solar simulating radiation (WG 320 filter) with its UVB component was theMost effective in inducing elastrosis.

Action Spectrum for Photocarcinogenesis

The wavelength dependence of the carcinogenicity of ultraviolet (UV) radiation needs to be known in order to assess the carcinogenic risks of various UV sources, most notably the different solar UV

Carbon monoxide signalling reduces photocarcinogenesis in the hairless mouse

TLDR
CO signalling was revealed to have previously unrecognized anti-carcinogenic functions in the skin, consistent with a protective modulation of the epidermal cytokines, which implies that the UVA waveband that produces CO physiologically in exposed skin, might likewise be found to have an anti-photocarc inogenic action.

WAVELENGTH DEPENDENCE OF HISTOLOGICAL, PHYSICAL, AND VISIBLE CHANGES IN CHRONICALLY UV‐IRRADIATED HAIRLESS MOUSE SKIN *

TLDR
The wavelength dependence spectra indicate that for all but one parameter measured (skin sagging), UV‐B radiation is considerably more efficient than UV‐A radiation in producing changes in the skin, and argues in favor of using broad spectrum photoprotective agents to shield the skin adequately from UV‐induced aging.

Near-visible-UV radiation delays UVB tumorigenesis.

Pretreatment with long-wave ultraviolet light inhibits ultraviolet-induced skin tumor development in hairless mice.

TLDR
Exposure with UV-A induced no visible changes of the skin, and subsequent microscopic examination revealed no measurable changes in epidermal thickness or melanin content, suggestingUV-A in addition to previously reported carcinogenic properties also may act as an antitumor agent.

Mexoryr SX Protects Against Solar‐Simulated UVR‐lnduced Photocarcinogenesis in Mice

TLDR
Although this study was explicitly designed as a safety test, the results also provide some clues about the efficacy of MexoryP SX in decreasing the probability of tumor development, and provide evidence in that it is safe for use in sunlight.

Spectral and dose dependence of ultraviolet radiation-induced immunosuppression.

TLDR
The established UV action spectra for a variety of cutaneous effects are outlined and the waveband and dose dependence of UV immunosuppression and its mechanisms are explored with a focus on in-vivo models.

Biological effects of narrow-band (311 nm TL01) UVB irradiation: a review.

...

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