AMPK activity regulates trafficking of mitochondria to the leading edge during cell migration and matrix invasion

Abstract

Cell migration is a complex behavior involving many energy-expensive biochemical events that iteratively alter cell shape and location. Mitochondria, the principal producers of cellular ATP, are dynamic organelles that fuse, divide, and relocate to respond to cellular metabolic demands. Using ovarian cancer cells as a model, we show that mitochondria… (More)
DOI: 10.1091/mbc.E16-05-0286

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Cite this paper

@inproceedings{Cunniff2016AMPKAR, title={AMPK activity regulates trafficking of mitochondria to the leading edge during cell migration and matrix invasion}, author={Brian Cunniff and Andrew N.J. McKenzie and Nicholas H. Heintz and Alan K. Howe}, booktitle={Molecular biology of the cell}, year={2016} }