• Corpus ID: 44799896

AMPK : A Bridge between Inflammation and Metabolism

  title={AMPK : A Bridge between Inflammation and Metabolism},
  author={Bo Chen and Haibo Zhu},
Hypercholesterolemia and low-grade inflammation are both basic factors that contribute to the genesis and progression of atherosclerosis. AMP-activated protein kinase (AMPK) is proposed to be a key regulator of cellular and organismal metabolism. Increased evidence shows that AMPK signaling can inhibit inflammatory responses. The macrophages play a diverse array of roles in atherogenesis, such as scavenge ring, immune modulation, and as a source of chemotactic molecules and cytokines. It has… 
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