AMPKα1 deficiency suppresses brown adipogenesis in favor of fibrogenesis during brown adipose tissue development.

Abstract

Brown adipose tissue (BAT) dissipates energy for thermogenesis which reduces or prevents obesity and metabolic dysfunction. AMP-activated protein kinase (AMPK) is a master regulator of energy metabolism and its activity is inhibited in the developing BAT due to obesity. We previously found that AMPK is required for brown fat development and thermogenic… (More)
DOI: 10.1016/j.bbrc.2017.06.149

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Cite this paper

@article{Zhao2017AMPK1DS, title={AMPKα1 deficiency suppresses brown adipogenesis in favor of fibrogenesis during brown adipose tissue development.}, author={Junxing Zhao and Qiyuan Yang and Lupei Zhang and Xingwei Liang and Xiaofei Sun and Bo Wang and Yanting Chen and Meijun Zhu and Min Du}, journal={Biochemical and biophysical research communications}, year={2017}, volume={491 2}, pages={508-514} }