AMPA receptor potentiators as cognitive enhancers.

  title={AMPA receptor potentiators as cognitive enhancers.},
  author={Michael J. O'Neill and Sophie L. Dix},
  journal={IDrugs : the investigational drugs journal},
  volume={10 3},
With an aging population, cognitive decline as a result of aging, Alzheimer's disease and other neurological conditions has become a major problem. Many of the current medications (eg, acetylcholinesterase inhibitors) for cognitive disorders show limited efficacy and are effective only in certain populations. Several other pharmacological pathways are therefore being explored in an attempt to develop superior medications. Glutamate and glutamate receptors are well recognized to play a key role… CONTINUE READING
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