AMPA receptor-mediated regulation of a Gi-protein in cortical neurons

@article{Wang1997AMPARR,
  title={AMPA receptor-mediated regulation of a Gi-protein in cortical neurons},
  author={Y Wang and Daniel L. Small and Danica B Stanimirovic and Paul Morley and Jon P. Durkin},
  journal={Nature},
  year={1997},
  volume={389},
  pages={502-504}
}
Excitatory synaptic transmission in the central nervous system is mediated primarily by the release of glutamate from presynaptic terminals onto postsynaptic channels gated by N -methyl-D-aspartate (NMDA) and α-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) receptors,. The myriad intracellular responses arising from the activation of the NMDA and AMPA receptors have previously been attributed to the flow of Ca2+ and/or Na + through these ion channels. Here we report that the binding of… Expand
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