AMPA receptor binding in adult guinea pig brain stem auditory nuclei after unilateral cochlear ablation.

@article{Suneja2000AMPARB,
  title={AMPA receptor binding in adult guinea pig brain stem auditory nuclei after unilateral cochlear ablation.},
  author={Sanoj K. Suneja and Steven J Potashner and Christina G Benson},
  journal={Experimental neurology},
  year={2000},
  volume={165 2},
  pages={355-69}
}
This study determined if an asymmetric hearing loss, due to unilateral cochlear ablation, could induce the regulation of intracellular AMPA receptors in brain stem auditory nuclei. In young adult guinea pigs, the high-affinity specific binding of [(3)H]AMPA was measured in the cochlear nucleus (CN), the superior olivary complex (SOC), and the auditory midbrain at 2-147 postlesion days. After correction for tissue shrinkage, changes in specific binding relative to that in age-matched unlesioned… CONTINUE READING
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