AMPA Receptor Expression Requirement During Long-Term Memory Retrieval and Its Association with mTORC1 Signaling.

@article{Pereyra2020AMPARE,
  title={AMPA Receptor Expression Requirement During Long-Term Memory Retrieval and Its Association with mTORC1 Signaling.},
  author={M. Pereyra and Ana Bel{\'e}n de Landeta and Juliana F{\'a}tima Dalto and C. Katche and Jorge H Medina},
  journal={Molecular neurobiology},
  year={2020}
}
  • M. Pereyra, Ana Belén de Landeta, +2 authors Jorge H Medina
  • Published 2020
  • Chemistry, Medicine
  • Molecular neurobiology
  • Recently, it was reported that mechanistic/mammalian target of rapamycin complex 1 (mTORC1) activity during memory retrieval is required for normal expression of aversive and non-aversive long-term memories. Here we used inhibitory-avoidance task to evaluate the potential mechanisms by which mTORC1 signaling pathway participates in memory retrieval. First, we studied the role of GluA-subunit trafficking during memory recall and its relationship with mTORC1 pathway. We found that pretest… CONTINUE READING

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