• Corpus ID: 37618955

AMPA, NMDA and GABAA receptor mediated network burst dynamics in cortical cultures in vitro

@article{Teppola2018AMPANA,
  title={AMPA, NMDA and GABAA receptor mediated network burst dynamics in cortical cultures in vitro},
  author={Heidi Teppola and Samora Okujeni and Marja-Leena Linne and U. Egert Department of Signal Processing and Tampere University of Technology and Tampere and Finland. and Bernstein Center FreiburgDepartment of Microsystems Engineering and Imtek and Albert-Ludwig University of Freiburg and Freiburg and Germany},
  journal={arXiv: Neurons and Cognition},
  year={2018}
}
In this work we study the excitatory AMPA, and NMDA, and inhibitory GABAA receptor mediated dynamical changes in neuronal networks of neonatal rat cortex in vitro. Extracellular network-wide activity was recorded with 59 planar electrodes simultaneously under different pharmacological conditions. We analyzed the changes of overall network activity and network-wide burst frequency between baseline and AMPA receptor (AMPA-R) or NMDA receptor (NMDA-R) driven activity, as well as between the latter… 

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