AMP-activated protein kinase regulates beta-catenin transcription via histone deacetylase 5.


AMP-activated protein kinase (AMPK) is a key regulator of energy metabolism; it is inhibited under obese conditions and is activated by exercise and by many anti-diabetic drugs. Emerging evidence also suggests that AMPK regulates cell differentiation, but the underlying mechanisms are unclear. We hypothesized that AMPK regulates cell differentiation via… (More)
DOI: 10.1074/jbc.M110.199372


5 Figures and Tables