AMP-activated protein kinase plays a role in the control of food intake.

  title={AMP-activated protein kinase plays a role in the control of food intake.},
  author={Ulrika Andersson and Karin Filipsson and Caroline R Abbott and Angela Woods and Kirsty L Smith and Stephen R. Bloom and David Carling and Caroline J. Small},
  journal={The Journal of biological chemistry},
  volume={279 13},
AMP-activated protein kinase (AMPK) is the downstream component of a protein kinase cascade that acts as an intracellular energy sensor maintaining the energy balance within the cell. The finding that leptin and adiponectin activate AMPK to alter metabolic pathways in muscle and liver provides direct evidence for this role in peripheral tissues. The hypothalamus is a key regulator of food intake and energy balance, coordinating body adiposity and nutritional state in response to peripheral… CONTINUE READING
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