AMP-activated protein kinase phosphorylates CtBP1 and down-regulates its activity.


CtBP is a transcriptional repressor which plays a significant role in the regulation of cell proliferation and tumor progression. It was reported that glucose withdrawal causes induction of Bax due to the dissociation of CtBP from the Bax promoter. However, the precise mechanism involved in the regulation of CtBP still remains unclear. In this study, we… (More)
DOI: 10.1016/j.bbrc.2012.12.117


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