AMP-Activated protein kinase is activated by the stimulations of G(q)-coupled receptors.

@article{Kishi2000AMPActivatedPK,
  title={AMP-Activated protein kinase is activated by the stimulations of G(q)-coupled receptors.},
  author={Kazuhiro Kishi and Tomoyuki Yuasa and Akio Minami and Masao Yamada and Akifumi Hagi and Hideki Hayashi and Bruce E. Kemp and Lee Alan Witters and Y. Ebina},
  journal={Biochemical and biophysical research communications},
  year={2000},
  volume={276 1},
  pages={16-22}
}
The AMP-activated protein kinase (AMPK) functions as a metabolic sensor that monitors cellular AMP and ATP levels. Platelet-activating factor (PAF) activates endogeneous AMPKalpha1 in Chinese hamster ovary cells expressing the PAF receptor coupled with both G(i) and G(q), but its activity was not inhibited after treatment with islet-activating protein. Norepinephrine and bradykinin also activated AMPKalpha1 in cells expressing the G(q)-coupled alpha(1b)-adrenergic receptor and bradykinin… CONTINUE READING
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