AMP-Activated Protein Kinase Plays an Important Evolutionary Conserved Role in the Regulation of Glucose Metabolism in Fish Skeletal Muscle Cells

@inproceedings{Magnoni2012AMPActivatedPK,
  title={AMP-Activated Protein Kinase Plays an Important Evolutionary Conserved Role in the Regulation of Glucose Metabolism in Fish Skeletal Muscle Cells},
  author={Leonardo J. Magnoni and Yoryia Vraskou and Arjan P. Palstra and Josep V Planas},
  booktitle={PloS one},
  year={2012}
}
AMPK, a master metabolic switch, mediates the observed increase of glucose uptake in locomotory muscle of mammals during exercise. AMPK is activated by changes in the intracellular AMP:ATP ratio when ATP consumption is stimulated by contractile activity but also by AICAR and metformin, compounds that increase glucose transport in mammalian muscle cells… CONTINUE READING