ALKBH5 Inhibits Pancreatic Cancer Motility by Decreasing Long Non-Coding RNA KCNK15-AS1 Methylation

@article{He2018ALKBH5IP,
  title={ALKBH5 Inhibits Pancreatic Cancer Motility by Decreasing Long Non-Coding RNA KCNK15-AS1 Methylation},
  author={Yuan He and H. Hu and Y. Wang and H. Yuan and Zi-peng Lu and Pengfei Wu and Dongfang Liu and L. Tian and Jie Yin and K. Jiang and Y. Miao},
  journal={Cellular Physiology and Biochemistry},
  year={2018},
  volume={48},
  pages={838 - 846}
}
  • Yuan He, H. Hu, +8 authors Y. Miao
  • Published 2018
  • Biology, Medicine
  • Cellular Physiology and Biochemistry
Background/Aims: Mounting evidence suggests that epitranscriptional modifications regulate multiple cellular processes. N6-Methyladenosine (m6A), the most abundant reversible methylation of mRNA, has critical roles in cancer pathogenesis. However, the mechanisms and functions of long non-coding RNA (lncRNA) methylation remain unclear. Pancreatic cancer resulted in 411,600 deaths globally in 2015. By the time of pancreatic cancer diagnosis, metastasis has often occurred in other parts of the… Expand
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