ALG-2 interacts with the amino-terminal domain of annexin XI in a Ca(2+)-dependent manner.

@article{Satoh2002ALG2IW,
  title={ALG-2 interacts with the amino-terminal domain of annexin XI in a Ca(2+)-dependent manner.},
  author={Hirokazu Satoh and Hideki Shibata and Yoshimi Nakano and Yasuyuki Kitaura and Masatoshi Maki},
  journal={Biochemical and biophysical research communications},
  year={2002},
  volume={291 5},
  pages={1166-72}
}
The apoptosis-linked protein ALG-2 is a Ca(2+)-binding protein that belongs to the penta-EF-hand protein family. ALG-2 forms a homodimer, a heterodimer with another penta-EF-hand protein, peflin, and a complex with its interacting protein, named AIP1 or Alix. By yeast two-hybrid screening using human ALG-2 as bait, we isolated a cDNA of a novel ALG-2-interacting protein, which turned out to be annexin XI. Deletion analysis revealed that ALG-2 interacted with the N-terminal domain of annexin XI… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 22 extracted citations

Annexin A11 is associated with pulmonary fibrosis in African American patients with sarcoidosis.

Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG • 2016

Similar Papers

Loading similar papers…