ALCAM/CD166 is up-regulated in low-grade prostate cancer and progressively lost in high-grade lesions.

Abstract

BACKGROUND Activated leukocyte cell adhesion molecule (ALCAM, CD166) is expressed in various tissues, including malignant melanoma, prostate cancer cell lines, and prostate cancer. We aimed to clarify the expression patterns of ALCAM in normal and malignant prostate tissue. METHODS RNA from 54 matched pairs of microdissected prostate tissue (tumor and… (More)

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