AKT-ions with a TWIST between EMT and MET

  title={AKT-ions with a TWIST between EMT and MET},
  author={Huifang Tang and Daniela Massi and Brian A. Hemmings and Mario Mandal{\`a} and Zhengqiang Hu and Andreas Wicki and Gongda Xue},
The transcription factor Twist is an important regulator of cranial suture during embryogenesis. Closure of the neural tube is achieved via Twist-triggered cellular transition from an epithelial to mesenchymal phenotype, a process known as epithelial-mesenchymal transition (EMT), characterized by a remarkable increase in cell motility. In the absence of Twist activity, EMT and associated phenotypic changes in cell morphology and motility can also be induced, albeit moderately, by other… CONTINUE READING
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