AKH-producing neuroendocrine cell ablation decreases trehalose and induces behavioral changes in Drosophila.

@article{Isabel2005AKHproducingNC,
  title={AKH-producing neuroendocrine cell ablation decreases trehalose and induces behavioral changes in Drosophila.},
  author={Guillaume Isabel and J Martin and Saad Chidami and Jan A Veenstra and Philippe Rosay},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2005},
  volume={288 2},
  pages={R531-8}
}
Adipokinetic hormone (AKH) is a metabolic neuropeptide principally known for its mobilization of energy substrates, notably lipid and trehalose during energy-requiring activities, such as flight and locomotion. Drosophila melanogaster AKH cell localization in corpora cardiaca, as in other insect species, was confirmed by immunoreactivity and by a genetic approach using the UAS/GAL4 system. To assess AKH general physiological rules, we ablated AKH endocrine cells by specifically driving the… CONTINUE READING
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