AK048794 maintains the mouse embryonic stem cell pluripotency by functioning as an miRNA sponge for miR-592.

  title={AK048794 maintains the mouse embryonic stem cell pluripotency by functioning as an miRNA sponge for miR-592.},
  author={Yang Zhou and Qing-Song Dai and Shiyong Zhu and Yuehua Han and Haitao Han and Bo Zhao and Rongrong Gao and Jun Zhang and Jing Zhang},
  journal={The Biochemical journal},
  volume={473 20},
MiR-592 has been identified as a neural-enriched microRNA, plays an important role in mNPCs differentiation, could induce astrogliogenesis differentiation arrest or/and enhance neurogenesis in vitro Previous studies showed that long noncoding RNAs (lncRNAs) were involved in the neuronal development and activity. To investigate the role of miR-592 in neurogenesis, we described the expression profile of lncRNAs in miR-592 knockout mouse embryonic stem cells (mESCs) and the corresponding normal… Expand
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