AIP1 acts with cofilin to control actin dynamics during epithelial morphogenesis.

@article{Chu2012AIP1AW,
  title={AIP1 acts with cofilin to control actin dynamics during epithelial morphogenesis.},
  author={Dandan Chu and Hanshuang Pan and P. N. Wan and Jing Wu and Jun Luo and Hong Zhu and Jiong Chen},
  journal={Development},
  year={2012},
  volume={139 19},
  pages={3561-71}
}
During epithelial morphogenesis, cells not only maintain tight adhesion for epithelial integrity but also allow dynamic intercellular movement to take place within cell sheets. How these seemingly opposing processes are coordinated is not well understood. Here, we report that the actin disassembly factors AIP1 and cofilin are required for remodeling of adherens junctions (AJs) during ommatidial precluster formation in Drosophila eye epithelium, a highly stereotyped cell rearrangement process… CONTINUE READING

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