AIP gene and familial isolated pituitary adenomas

@article{Ozfirat2010AIPGA,
  title={AIP gene and familial isolated pituitary adenomas},
  author={Zehra Ozfirat and M{\'a}rta Korbonits},
  journal={Molecular and Cellular Endocrinology},
  year={2010},
  volume={326},
  pages={71-79}
}
  • Zehra Ozfirat, Márta Korbonits
  • Published in
    Molecular and Cellular…
    2010
  • Medicine, Biology
  • Familial pituitary adenomas occurr in the classical syndromes of MEN1 and Carney Complex as well as in Familial Isolated Pituitary Adenomas (FIPA), an autosomal dominant disease with incomplete penetrance. In some families and also rarely in sporadic tumours germline mutations of a gene located on chromosome 11q13 known as the aryl hydrocarbon receptor interacting protein have been found. This article discusses the AIP mutations in these groups and the different molecular interactions of AIP… CONTINUE READING

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