AGA technical review on irritable bowel syndrome.

@article{Drossman2002AGATR,
  title={AGA technical review on irritable bowel syndrome.},
  author={Douglas A. Drossman and Michael Joseph Camilleri and Emeran A. Mayer and William E. Whitehead},
  journal={Gastroenterology},
  year={2002},
  volume={123 6},
  pages={
          2108-31
        }
}
Abstract The irritable bowel syndrome (IBS) is part of the larger group of functional gastrointestinal (GI) disorders that, despite differences in location and symptom patterns, share common features with regard to their motor and sensory physiology, central nervous system (CNS) relationships, and the approach to patient care.1 IBS is a functional bowel disorder characterized by symptoms of abdominal pain or discomfort that is associated with disturbed defecation.2 This disorder is highly… Expand

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Our understanding of the pathophysiology of irritable bowel syndrome (IBS) has evolved from a disorder of motility to a more integrated understanding of enhanced motility and visceralExpand
Irritable bowel syndrome: the influence of psychological factors on the symptom complex.
TLDR
It is suggested that anxiety may be more important in the maintenance of the IBS symptom complex, and depression moreImportant in determining intercurrent fluctuations in perceived distress and illness behaviour in response to adverse life events. Expand
The Irritable Bowel Syndrome: Long-Term Prognosis and the Physician-Patient Interaction
TLDR
The irritable bowel syndrome is evaluated by following a cohort of patients from a community using their medical records, after they were initially diagnosed with IBS according to current criteria, to objectively assess whether the physicianpatient interaction was associated with prognosis. Expand
Mind over matter in the postinfective irritable bowel
TLDR
In a regression analysis, pre-existent life stress and hypochondriasis were the strongest predictors of the IBS+ group, and the development of IBS-like symptoms was not explained by illness behaviours. Expand
Jejunal sensorimotor dysfunction in irritable bowel syndrome: clinical and psychosocial features.
TLDR
In IBS, abnormal postprandial jejunal motor activity is related to jeJunal mechanoreceptor-related hypersensitivity, and such sensorimotor dysfunction has a specific psychological profile. Expand
Altered small bowel motility in irritable bowel syndrome is correlated with symptoms.
TLDR
It is concluded that motility of the small intestine is modified in some patients with IBS and that certain motor patterns are related to their symptoms. Expand
Health-related quality of life and associated psychosocial factors in irritable bowel syndrome: A review
TLDR
Significantly lower scores on both the physical and mental health scales of the Short Form-36 are reported for individuals with IBS symptoms as compared with asymptomatic controls and US norms. Expand
Influence of drug treatment on the irritable bowel syndrome and its interaction with psychoneurotic morbidity
TLDR
There is no direct relationship between psychoneurotic illness and IBS, but the presence of the former has an adverse effect on the shortterm outcome of the bowel disorder. Expand
The irritable bowel syndrome: review and a graduated multicomponent treatment approach.
TLDR
It is suggested that the physician also assess the severity of the illness based on its symptomatic and functional features and the patient's behavioral response, allowing a graduated treatment approach that emphasizes education, reassurance, and dietary adjustment for mild symptoms. Expand
Functional dyspepsia and irritable bowel syndrome: is there a common pathophysiological basis?
TLDR
Differences in the pattern and localization of symptoms probably do not reflect differences in small intestinal sensory thresholds, and functional dyspepsia and IBS cannot be distinguished on the basis of altered small intestinal mechanosensitive thresholds. Expand
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