ADIPOQ -11377C>G Polymorphism Increases the Risk of Adipokine Abnormalities and Child Obesity Regardless of Dietary Intake.

@article{Gajewska2016ADIPOQP,
  title={ADIPOQ -11377C>G Polymorphism Increases the Risk of Adipokine Abnormalities and Child Obesity Regardless of Dietary Intake.},
  author={Joanna Gajewska and Alina Kuryłowicz and Jadwiga Ambroszkiewicz and Ewa J. Mierzejewska and Magdalena Chełchowska and Katarzyna Szamotulska and Halina Weker and Monika Puzianowska-Kuźnicka},
  journal={Journal of pediatric gastroenterology and nutrition},
  year={2016},
  volume={62 1},
  pages={122-9}
}
OBJECTIVE The aim of the present study was to verify whether selected functional single nucleotide polymorphisms in LEP, LEPR, and ADIPOQ loci are associated with the development of obesity and serum levels of the respective adipokines in prepubertal white children with obesity. METHODS Frequencies of -2548G>A LEP (rs7799039), Q223R (rs1137101) and K656N (rs8129183) LEPR, and -11377C>G (rs266729) and -11426A>G (rs16861194) ADIPOQ polymorphisms were analyzed by restriction fragment length… CONTINUE READING