ADENOSINE RELEASE IN THE ANOXIC TURTLE BRAIN : A POSSIBLE MECHANISM FOR ANOXIC SURVIVAL

@inproceedings{Nilsson2005ADENOSINERI,
  title={ADENOSINE RELEASE IN THE ANOXIC TURTLE BRAIN : A POSSIBLE MECHANISM FOR ANOXIC SURVIVAL},
  author={Goran E Nilsson and Peter L. Lutz},
  year={2005}
}
In the brain of most vertebrates, anoxia or ischaemia rapidly causes a fall in ATP levels and in the activity of the Na + /K + pump, resulting in general depolarization followed by a cascade of catastrophic events (Hansen, 1985; Hochachka, 1986). By contrast, the brain of freshwater turtles survives many hours of complete anoxia at 25°C. Hence, the turtle brain has become the archetype of an anoxia-tolerant brain, and considerable efforts have been devoted to finding the mechanisms underlying… CONTINUE READING
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