ADC histograms predict response to anti-angiogenic therapy in patients with recurrent high-grade glioma

@article{Nowosielski2010ADCHP,
  title={ADC histograms predict response to anti-angiogenic therapy in patients with recurrent high-grade glioma},
  author={Martha Nowosielski and Wolfgang Recheis and Georg G{\"o}bel and {\"O}zg{\"u}r G{\"u}ler and Gerd Tinkhauser and Herwig Kostron and Michael Schocke and Thaddaeus Gotwald and Guenther Stockhammer and Markus Hutterer},
  journal={Neuroradiology},
  year={2010},
  volume={53},
  pages={291-302}
}
The purpose of this study is to evaluate apparent diffusion coefficient (ADC) maps to distinguish anti-vascular and anti-tumor effects in the course of anti-angiogenic treatment of recurrent high-grade gliomas (rHGG) as compared to standard magnetic resonance imaging (MRI). This retrospective study analyzed ADC maps from diffusion-weighted MRI in 14 rHGG patients during bevacizumab/irinotecan (B/I) therapy. Applying image segmentation, volumes of contrast-enhanced lesions in T1 sequences and of… CONTINUE READING