ADAMTS16 mutations sensitize ovarian cancer cells to platinum-based chemotherapy

@inproceedings{Yasukawa2016ADAMTS16MS,
  title={ADAMTS16 mutations sensitize ovarian cancer cells to platinum-based chemotherapy},
  author={Maya Yasukawa and Yuexin Liu and Limei Hu and David Cogdell and Kshipra M. Gharpure and Sunila Pradeep and Archana Sidalaghatta Nagaraja and Anil Sood and Wei Zhang},
  booktitle={Oncotarget},
  year={2016}
}
Ovarian cancer is one of the most lethal malignant tumors in women. The prognosis of ovarian cancer patients depends, in part, on their response to platinum-based chemotherapy. Our recent analysis of genomics and clinical data from the Cancer Genome Atlas demonstrated that somatic mutations of ADAMTS 1, 6, 8, 9, 15, 16, 18 and L1 genes were associated with… CONTINUE READING