ADAMTS13 Gene Mutations in Children with Hemolytic Uremic Syndrome

Abstract

We investigated ADAMTS13 activity as well as the ADAMTS13 gene mutation in children with hemolytic uremic syndrome (HUS). Eighteen patients, including 6 diarrhea- negative (D-HUS) and 12 diarrhea-associated HUS (D+HUS) patients, were evaluated. The extent of von Willebrand factor (VWF) degradation was assayed by multimer analysis, and all exons of the… (More)
DOI: 10.3349/ymj.2011.52.3.530

2 Figures and Tables

Topics

  • Presentations referencing similar topics