ADAMTS-1 is involved in normal follicular development, ovulatory process and organization of the medullary vascular network in the ovary.

@article{Shozu2005ADAMTS1II,
  title={ADAMTS-1 is involved in normal follicular development, ovulatory process and organization of the medullary vascular network in the ovary.},
  author={M. Shozu and N. Minami and H. Yokoyama and M. Inoue and H. Kurihara and K. Matsushima and K. Kuno},
  journal={Journal of molecular endocrinology},
  year={2005},
  volume={35 2},
  pages={
          343-55
        }
}
To clarify the role of disintegrin-like and metalloproteinase with thrombospondin type I motifs-1 (ADAMTS-1) in ovarian function, we examined abnormalities in ovulatory processes, folliculogenesis and the vascular system of ADAMTS-1 null ovaries. First, when immature female mice were treated with pregnant mare serum gonadotropin (PMSG)/human chorionic gonadotropin (hCG), the number of ovulated oocytes was markedly decreased in ADAMTS-1 null mice in comparison to ADAMTS-1 (+/-) controls. The… Expand
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References

SHOWING 1-10 OF 38 REFERENCES
Adamts-1 Is Essential for the Development and Function of the Urogenital System1
  • 161
  • PDF
Progesterone-regulated genes in the ovulation process: ADAMTS-1 and cathepsin L proteases.
  • 454
  • PDF
Processing and Localization of ADAMTS-1 and Proteolytic Cleavage of Versican during Cumulus Matrix Expansion and Ovulation*
  • 244
  • Highly Influential
  • PDF
ADAMTS-1: a metalloproteinase-disintegrin essential for normal growth, fertility, and organ morphology and function.
  • 280
  • PDF
Abortive expansion of the cumulus and impaired fertility in mice lacking the prostaglandin E receptor subtype EP(2).
  • H. Hizaki, E. Segi, +9 authors A. Ichikawa
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 1999
  • 391
  • PDF
Vascular endothelial growth factor receptor 2-mediated angiogenesis is essential for gonadotropin-dependent follicle development.
  • 70
  • PDF
Cyclic Changes in the Matrix Metalloproteinase System in the Ovary and Uterus1
  • 206
  • PDF
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