ADAMTS‐13 and von Willebrand factor: a dynamic duo

@inproceedings{South2018AA,
  title={
ADAMTS‐13 and von Willebrand factor: a dynamic duo},
  author={Kieron South and David A. Lane},
  booktitle={Journal of thrombosis and haemostasis : JTH},
  year={2018}
}
von Willebrand factor (VWF) is a key player in hemostasis, acting as a carrier for factor VIII and capturing platelets at sites of vascular damage. To capture platelets, it must undergo conformational changes, both within its A1 domain and at the macromolecular level through A2 domain unfolding. Its size and this function are regulated by the… CONTINUE READING