ADAM7 is associated with epididymosomes and integrated into sperm plasma membrane

@article{Oh2009ADAM7IA,
  title={ADAM7 is associated with epididymosomes and integrated into sperm plasma membrane},
  author={J. Oh and Cecil Han and C. Cho},
  journal={Molecules and Cells},
  year={2009},
  volume={28},
  pages={441-446}
}
During epididymal transit, mammalian sperm acquire selected proteins secreted by the epididymis. We previously showed that a disintegrin and metalloprotease (ADAM) 7 is expressed specifically in the epididymis and transferred to the sperm surface during epididymal transit. Here, we show that mouse ADAM7 secreted to the epididymal lumen is associated with membranous vesicles known as epididymosomes. Furthermore, we found that ADAM7 can be transferred directly from epididymal vesicles to sperm… Expand
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