ADAM19 expression in human nephrogenesis and renal disease: associations with clinical and structural deterioration.

@article{Melenhorst2006ADAM19EI,
  title={ADAM19 expression in human nephrogenesis and renal disease: associations with clinical and structural deterioration.},
  author={Wynand B. W. H. Melenhorst and Marius C. Van den Heuvel and Albertus Timmer and Sippie Huitema and Marian L.C. Bulthuis and Wim Timens and Harry van Goor},
  journal={Kidney international},
  year={2006},
  volume={70 7},
  pages={1269-78}
}
ADAM19, an enzyme from the ADAM (a disintegrin and metalloproteinase) family, is involved in various cell-cell and cell-matrix interactions. It can cleave epidermal growth factor (EGF)-like growth factors, such as heparin-binding (HB)-EGF and neuregulin (NRG), from the cell membrane. ADAM-mediated EGF receptor activation is crucial in the development of… CONTINUE READING