ADAM-9, ADAM-15, and ADAM-17 are upregulated in macrophages in advanced human atherosclerotic plaques in aorta and carotid and femoral arteries--Tampere vascular study.

@article{Oksala2009ADAM9AA,
  title={ADAM-9, ADAM-15, and ADAM-17 are upregulated in macrophages in advanced human atherosclerotic plaques in aorta and carotid and femoral arteries--Tampere vascular study.},
  author={Niku K. J. Oksala and Mari Levula and Nina Airla and Markku Pelto-Huikko and Rebekka M Ortiz and Otso J{\"a}rvinen and J. Salenius and Bilge Ozsait and Evrim Komurcu-Bayrak and Nihan Erginel-Unaltuna and Ari-Pekka J Huovila and Leena Kyt{\"o}m{\"a}ki and Juhani T. Soini and Mika K{\"a}h{\"o}nen and Pekka J. Karhunen and Reijo Laaksonen and Terho Lehtim{\"a}ki},
  journal={Annals of medicine},
  year={2009},
  volume={41 4},
  pages={279-90}
}
BACKGROUND AND AIMS The expression of disintegrin and metalloprotease ADAM-9, ADAM-15, and ADAM-17 has been associated with cell-cell, cell-platelet, and cell-matrix interactions and inflammation. They are possibly implicated in the pathophysiology of atherosclerosis. METHODS AND RESULTS Whole-genome expression array and quantitative real-time polymerase chain reaction (PCR) analysis confirmed that ADAM-9, ADAM-15, and ADAM-17 are upregulated in advanced human atherosclerotic lesions in… CONTINUE READING
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