AChE and the amyloid precursor protein (APP) - Cross-talk in Alzheimer's disease.


The amyloid precursor protein (APP) and acetylcholinesterase (AChE) are multi-faceted proteins with a wide range of vital functions, both crucially linked with the pathogenesis of Alzheimer's disease (AD). APP is the precursor of the Aβ peptide, the pathological agent in AD, while AChE is linked to its pathogenesis either by increasing cholinergic deficit… (More)
DOI: 10.1016/j.cbi.2016.04.009


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Citations per Year

Citation Velocity: 12

Averaging 12 citations per year over the last 2 years.

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