ACUTE HAEMOLYTIC ANAEMIA DUE TO PHENAZOPYRIDINE HYDROCHLORIDE IN G-6-PD DEFICIENT SUBJECT

@article{Mercieca1982ACUTEHA,
  title={ACUTE HAEMOLYTIC ANAEMIA DUE TO PHENAZOPYRIDINE HYDROCHLORIDE IN G-6-PD DEFICIENT SUBJECT},
  author={Jane Mercieca and MaryF. Clarke and MalcolmE. Phillips and J. Harrison Curtis},
  journal={The Lancet},
  year={1982},
  volume={320}
}
6 Citations
Review and drug therapy implications of glucose‐6‐phosphate dehydrogenase deficiency
  • K. Belfield, E. Tichy
  • Medicine, Biology
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
  • 2018
TLDR
G6PD deficiency should be considered in patients who experience acute hemolysis after exposure to known oxidative medications, infection, or ingestion of fava beans.
Identification of New FLT3 Inhibitors That Potently Inhibit AML Cell Lines via an Azo Click-It/Staple-It Approach.
TLDR
A new class of FLT3 inhibitors is reported, which potently inhibit the proliferation of acute myeloid leukemia (AML) cells at nanomolar concentrations.
Haematological Effects of Non-Narcotic Analgesics
TLDR
It now appears that patients may develop antibodies whose specificity depends on a drug as well as on a component of the blood cell membrane, which would be explained by the autoantigenic constituent of the drug-autoantigen complex.
Medications and Glucose-6-Phosphate Dehydrogenase Deficiency
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common human enzyme defect and one of the most common genetic disorders worldwide, with an estimated 400 million people worldwide
Heinz-Body Hemolytic Anemia Associated with Phenazopyridine and Sulfonamide
TLDR
This case should sensitize the clinician to the development of drug-induced oxidative hemolytic anemia, its clinical features, and its reversibility.
Phenazopyridine-Induced Hemolytic Anemia in G-6-PD Deficiency
TLDR
A case in which symptoms of pheny toin toxicity began two weeks after the initiation of amiodarone therapy and continued to increase until the phenytoin dose was reduced four weeks after concurrent therapy began, and a rapid resolution of all symptoms of toxicity followed.

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