ACUTE AND CHRONIC PITUITARY FAILURE RESEMBLING SHEEHAN'S SYNDROME FOLLOWING BITES BY RUSSELL'S VIPER IN BURMA

@article{TunPe1987ACUTEAC,
  title={ACUTE AND CHRONIC PITUITARY FAILURE RESEMBLING SHEEHAN'S SYNDROME FOLLOWING BITES BY RUSSELL'S VIPER IN BURMA},
  author={Tun-Pe and David A. Warrell and Tin-Nu-Swe and RodneyE. Phillips and R Andrew Moore and Myint-Lwin and C. W. Burke},
  journal={The Lancet},
  year={1987},
  volume={330},
  pages={763-767}
}
Pituitary function was investigated in 9 patients in shock after Russell's viper bites and in 24 individuals who had been severely envenomed 2 weeks to 24 years previously. 3 out of 9 patients had hypoglycaemia and inappropriately low serum cortisol, plasma growth hormone, and plasma prolactin concentrations. 4 who died had pituitary haemorrhage and 1 had adrenal haemorrhage as well. Of the 24 who had apparently recovered from bites, 7 had clinical features of hypopituitarism and no response in… 
The anterior pituitary, snakebite and Sheehan's syndrome.
  • C. Burke
  • Medicine
    The Quarterly journal of medicine
  • 1990
TLDR
The Hammersmith group with a different set of Burmese researchers have confirmed the findings, showing bite by this viper to be a common cause of anterior pituitary failure in Burma, and the empirical use of high-dose steroids in India rests on reduced mortality in rats.
Acute pituitary insufficiency and hypokalaemia following envenoming by Russell's viper (Daboia russelii) in Sri Lanka: Exploring the pathophysiological mechanisms.
TLDR
The association of acute pituitary insufficiency and hypokalaemia following Russell's viper envenoming in Sri Lanka is described and the literature is reviewed in order to understand its pathophysiological basis.
Chronic Pituitary Failure Resembling Sheehan's Syndrome following a Bite of Russell's Viper
TLDR
A case of hypopituitarism with clinical, endocrine and magnetic resonance (MR) imaging studies occurring as a delayed complication of snake bite is described.
ACQUIRED ECTOPIC POSTERIOR PITUITARY BRIGHT SPOT DUE TO VASCULOTOXIC SNAKEBITE.
TLDR
EPP in the index case was probably due to the "axonal dieback" phenomenon and subsequent regeneration of the axons at a more caudal site, and expands the spectrum of envenomation-induced hypopituitarism.
Psychosis in Secondary Empty Sella Syndrome following a Russell's Viper Bite
TLDR
A unique case of psychosis in clear consciousness in a case of hypopituitarism due to the secondary empty sella syndrome following a Russell's viper bite which was untreated and presented with psychotic symptoms for past 13 years following the snake bite.
Predictors of hypopituitarism due to vasculotoxic snake bite with acute kidney injury
TLDR
Hypopituitarism can develop as early as 7 days following snake bite and should be evaluated for particularly in younger subjects, especially those requiring increasing number of sessions of hemodialysis and in subjects with abnormal 20 min WBCT at presentation.
Development of renal function abnormalities following bites by Russell's vipers (Daboia russelii siamensis) in Myanmar.
TLDR
Renal function was monitored in 24 patients with systemic envenoming following proven Russell's viper bite and albuminuria, found only in patients who became systemically envenomed, was associated with high fractional sodium excretion in those who developed acute oliguric renal failure.
Burmese Russell's viper venom causes hormone release from rat pituitary cells in vitro.
TLDR
It is concluded that Burmese Russell's viper venom has direct effects on pituitary hormone release in vitro, and whether these effects contribute to its known actions in vivo on the function of the pituitaries remains to be established.
Delayed hypopituitarism following Russell’s viper envenomation: a case series and literature review
TLDR
DHP is an important complication of RVE, and a delay in its diagnosis is associated with significant morbidity, so patients with RVE should be followed up for a long term to identify DHP.
Contribution of focal haemorrhage and microvascular fibrin deposition to fatal envenoming by Russell's viper (Vipera russelli siamensis) in Burma.
TLDR
Clinical features included local swelling, spontaneous systemic bleeding, defibrination, shock, cardiac arrhythmia, hypoglycaemia, coma and oliguria, and acute tubular necrosis in three young farmers who died after being bitten by Russell's vipers in Burma.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 13 REFERENCES
BITES BY RUSSELL'S VIPER (VIPERA RUSSELLI SIAMENSIS) IN BURMA: HAEMOSTATIC, VASCULAR, AND RENAL DISTURBANCES AND RESPONSE TO TREATMENT
TLDR
The Burma Pharmaceutical Industry monospecific antivenom was rapidly effective in restoring blood coagulability but did not prevent the development of renal failure even when given within 4 h of the bite.
Histological and ultrastructural changes of the kidney in renal failure after viper envenomation.
  • M. Aung-khin
  • Medicine
    Toxicon : official journal of the International Society on Toxinology
  • 1978
Abstract Forty experimental animals injected with lethal doses of Russell's viper venom and seven human victims of viper snake bite were studied in order to elucidate the pathogenesis of renal
II. The pathology of epidemic haemorrhagic fever
TLDR
The kidneys, pituitary, heart and suprarenals are most affected, and areas of necrosis are sometimes seen, and appear to be secondary to the vascular disorganization which occurs.
Unusual Complication of Snake Bite: Hypopituitarism after Viper Bites
TLDR
Three people were seen later with manifestations of panhypopituitarism as a complication of snake bite in the Little Flower Hospital, Angamally during a period from June 1966, to July, 1974.
Post‐partum Necrosis of the Anterior Pituitary; Pathological and Clinical Aspects
in Zentralb. ges. N e w o l . Psychiat., 1937, Ixxxv, 208. xii, r j ; Rev. F r a r ~ ~ . Eiidocrin., 1937, xv, 291. , /own. Nzrv. Ment. Dis., 1936, lxxxiii, 166. R d l . Soc. Mbd. Hdp. Paris, 1936,
Pathology of epidemic hemorrhagic fever.
Excerpt From the standpoint of Western medicine there has been little or no experience with epidemic hemorrhagic fever.1Since the early 1930's there has been a continually developing awareness by R...
The syndrome of hypopituitarism.
...
1
2
...