ACTIVATION OF EGF RECEPTORS MEDIATES PULMONARY VASOCONSTRICTION INDUCED BY RESIDUAL OIL FLY ASH

@article{Huang2002ACTIVATIONOE,
  title={ACTIVATION OF EGF RECEPTORS MEDIATES PULMONARY VASOCONSTRICTION INDUCED BY RESIDUAL OIL FLY ASH},
  author={Yuh Chin Huang and Weidong Wu and Andrew J. Ghio and Jacqueline D. Carter and Robert A Silbajoris and Robert B. Devlin and James M. Samet},
  journal={Experimental Lung Research},
  year={2002},
  volume={28},
  pages={19 - 38}
}
Residual oil fly ash (ROFA)is a constituent of pollutant particles that can producelung injury and activate protein tyrosine phosphorylation cascade. In this study, we determined whether or not protein tyrosine phosphorylation caused lung injury, and if so, identified critical tyrosine phosphorylated proteins that mediated the injury. ROFA was instilled intratracheally into perfused rabbit lungs and injury responses, including increase in pulmonary artery pressure (Ppa), lung weight gain, as… 
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  • Nik Newland, A. Richter
  • Biology, Medicine
    Toxicology in vitro : an international journal published in association with BIBRA
  • 2008
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