ACTH-dependent proteolytic activity of a novel phosphoprotein (p43) intermediary in the activation of phospholipase A2 and steroidogenesis.

Abstract

Arachidonic acid (AA) and the lipooxygenase products have been shown to play an obligatory role in the mechanism of action of LH and ACTH, at a point after cAMP-dependent phosphorylation. We have demonstrated the presence of a phosphoprotein (p43) that responds to cAMP signals to induce steroid synthesis in adrenocortical tissue, an effect that is blocked… (More)

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Cite this paper

@article{Cymeryng1995ACTHdependentPA, title={ACTH-dependent proteolytic activity of a novel phosphoprotein (p43) intermediary in the activation of phospholipase A2 and steroidogenesis.}, author={Cora Beatriz Cymeryng and C. C. S. C. Paz and Laura A Dada and Fabiana Cornejo Maciel and Michael Neuman and Pablo G. Mele and Carla V Finkielstein and Antonio Solano and Catalina M{\'e}ndez and M S Park}, journal={Endocrine research}, year={1995}, volume={21 1-2}, pages={281-8} }