ACQUIRED IMMUNODEFICIENCY SYNDROME IN RWANDA

@article{Perre1984ACQUIREDIS,
  title={ACQUIRED IMMUNODEFICIENCY SYNDROME IN RWANDA},
  author={Philippe Van de Perre and Ph. Lepage and Philippe Kestelyn and A. C. Hekker and Dominique Rouvroy and Joseph Bogaerts and J Kayihigi and J. P. Butzler and Nathan Clumeck},
  journal={The Lancet},
  year={1984},
  volume={324},
  pages={62-65}
}

THE AIDS PROBLEM IN AFRICA

Endemic african kaposi's sarcoma is not associated with immunodeficiency

TLDR
Twenty‐seven histologically confirmed Kaposi sarcoma patients resident in the Kivu Lake area of eastern Zaire were examined for immune competence and evidence of immune suppression among KS patients was found and there were no significant differences in the immune status between KS patients and controls.

Acquired immunodeficiency syndrome and human immunodeficiency virus infection in Bujumbura, Burundi.

Pathogenetic Mechanisms of the Acquired Immune Deficiency Syndrome

A new syndrome characterized by a rare malignancy, Kaposi’s sarcoma, Pneumocystis carinii pneumonia, and other severe opportunistic infections was reported by the Centers for Disease Control (CDC),

AIDS in Africa: a retrospective.

  • T. Quinn
  • Medicine
    Bulletin of the World Health Organization
  • 2001
TLDR
It was evident by 1986 that HIV/ AIDS was an escalating epidemic in central Africa with an estimated annual incidence of AIDS of 550-1000 cases per million adults, with 1-18% of healthy blood donors and pregnant women infected with HIV, and 27-88% of female commercial sex workers serologically positive for HIV.

The acquired immunodeficiency syndrome in Haiti.

TLDR
Patients in Haiti with the acquired immunodeficiency syndrome differed from age- and sex-matched siblings and friends in the number of heterosexual contacts and receipt of intramuscular injections, which represent potential modes of transmission of infection with the human T-lymphotropic virus type III.

Seroepidemiological studies of HTLV-III antibody prevalence among selected groups of heterosexual Africans.

TLDR
It is suggested that human T-cell lymphotropic virus type III infection has already spread extensively into the general African population and that female prostitutes could be an important human reservoir of AIDS virus in the heterosexual population.

Pulmonary complications of human immunodeficiency virus infection in Bujumbura, Burundi.

TLDR
HIV infection is a major risk factor for the development of acute respiratory diseases in adults of sufficient severity to require hospitalization in Bujumbura, where exposure to virulent bacterial pathogens is ubiquitous.

Acquired Immunodeficiency Syndrome (AIDS) in Africa

TLDR
Although the mode of transmission of AIDS in Africa remains unknown the possible role of scarifications unsterile injections and transfusions needs investigation.
...

References

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Acquired immunodeficiency syndrome in African patients.

TLDR
This syndrome in patients originating in Central Africa is similar to the acquired immunodeficiency syndrome reported in American patients.

National case-control study of Kaposi's sarcoma and Pneumocystis carinii pneumonia in homosexual men: Part 2. Laboratory results.

TLDR
An outbreak of Kaposi's sarcoma and P. carinii pneumonia in homosexual men was found to be associated with certain aspects of lifestyle, including a greater number of male sex partners per year, exposure to feces during sex, history of syphilis and non-B hepatitis, treatment for enteric parasites, and use of various illicit substances.

Indirect immunofluorescence test for detection of IgM antibodies to cytomegalovirus.

TLDR
Sera from 63 patients with a rise in titer of antibody to CMV, indicated by complement fixation, were IgM-positive, but yielded negative results on the Paul-Bunnell-Davidsohn test for infectious mononucleosis, which could be made several weeks earlier than by the complement-fixation test.

Fluorescent treponemal antibody-absorption (FTA-ABS) test for syphilis.

The development of the fluorescent treponemal antibody-absorption (FTA-ABS) test 1 has been the result of continued attempts to improve the original FTA procedures, 2,3 in terms of sensitivity and

Characterization of immunoregulatory T lymphocytes during ageing by monoclonal antibodies.

TLDR
The responses of PBMC to phytohaemagglutinin extent (PHA), concanavalin A (Con A) and pokeweed mitogen (PWM) are reduced to the same extent in ageing male and female subjects when compared to young adults.

THE GONOCOCCAL COMPLEMENT-FIXATION TEST

TLDR
From the shape of the bone one can see that the pain was caused by the bone presenting at the pyloric orifice with the two prongs in front, so that it was impossible for it to pass in this way.